https://www.pebblelabs.com/home daily 1.0 2025-10-01 https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/f1e2d622-a467-4a2f-818a-01d727a6a4b8/4.png Home https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1678406229716-S6Z2QWE227DRY6FSBSP6/unsplash-image-h-CGKH94oIs.jpg Home https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1678406014468-2IPXRIFZZR09HED06APW/unsplash-image-ettyLtH2GjU.jpg Home https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1629313734712-39N61R8DPEQ82C99QMV0/tomatoes.png Home https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1629295196632-I9E71AM8HO9XLCK15D4R/2.png Home - Pebble Labs is creating safe and effective biological solutions to sustainably protect yields and quality in food production. We harness naturally occurring microbes from crops to deliver the power of RNA for solutions that target formidable pests and diseases. https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/f02f3548-19c5-436c-a0a4-37e2c11c250e/feed+the+world.png Home - Feeding 2 billion more people by 2050 will require 50% more production per acre, and climate change threatens food production in new ways. https://www.pebblelabs.com/directedbiotics daily 0.75 2023-03-10 https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1629483031146-8CCMOC31Q52H5CI00ESP/DB+diagram.png Directed Biotics™ https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/fdf40063-0575-4a5a-b4b3-94d82c8d7842/1.png Directed Biotics™ - Microbes Do The Heavy Lifting CONTINUOUS PRODUCTION OF RNAi IN HOST Pebble Lab's Directed Biotics™ microbes are living biofactories for RNAi directly in the host STABILITY IN THE POND / FIELD Using naturally symbiotic microbes exploits inherent microbial stability through host-microbe relationship TARGETED IMPACT Directed Biotics™ is designed to avoid unwanted off-target effects, with no persistence or harm in the environment https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/17669119-4ce8-430e-ada6-78155aa79bc9/edited+microscope.jpg Directed Biotics™ - The Role of Microbiomes Since Pebble Labs’ technology uses naturally occurring microbes to deliver RNA, Directed Biotics™ is broadly applicable to plants or animals. The microbes we use are selected from the microbiome of the plant or animal of interest, and are added back to the microbiome as Directed Biotics™ to provide protection against diseases or pests. Our first products are in shrimp aquaculture and produce such as potatoes and tomatoes. https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1629230417739-SNU313W07VSLY718PVO8/IMG-1201.jpg Directed Biotics™ - Directed Biotics™ products Pebble has a strong international patent portfolio to protect its novel Directed Biotics™ technology. We are advancing in our research and development program and are currently planning pre-commercial activities. https://www.pebblelabs.com/ourstory daily 0.75 2025-10-01 https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/e3ff12a1-1794-4e90-a7bf-e5bc48128b32/24.png Our Story - Who We Are Pebble Labs was founded to develop a novel, sustainable, and broadly applicable biological platform focused on plant health for food production. Our platform technology delivers safe and effective biological solutions that sustainably address the most significant challenges for global food production. We harness naturally occurring microbes from crops of interest to deliver the power of RNA to sustainably protect yields and quality through solutions that target formidable pests and diseases. We constantly draw inspiration from our home in New Mexico, an ancient land that is home to many modern innovations, where nature and technology thrive together. https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1629223234537-MMIIOMR72FOZ5SRQ5SCV/unsplash-image-4x6dxnVMRWE.jpg Our Story - “Technology transfer success stories like Pebble Labs in Los Alamos are a great example of innovation taking root in New Mexico.” — Governor Michelle Lujan Grisham https://www.pebblelabs.com/ourteam daily 0.75 2026-02-25 https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/d618e89e-8f4d-42a3-ac03-6c82baa0db84/Johnny_Sena_cropped_2.png Our Team https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/ce098ae7-d298-47fc-b9d5-1387c3bfb77b/Kelly_Schilling_cropped_V2.png Our Team https://www.pebblelabs.com/contact daily 0.75 2025-10-01 https://www.pebblelabs.com/how-rna-works daily 0.75 2021-12-14 https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1629312275858-7VDPVUPSR0VTKXYP5FTE/RNA+runs+the+world.png How RNA Works https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/7c21de55-a704-4090-ac15-45fa9d82e9d7/edited+sample.jpg How RNA Works Over the last few decades, there has been an explosion of uses for RNA biology. https://www.pebblelabs.com/biologicals daily 0.75 2021-12-16 https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/8dc4a15a-a237-470b-adfc-449c15cbd631/edited+lab+plant.jpg Biologicals - Pebble Labs uses naturally occurring microbes from crops of interest to deliver the power of RNA for solutions that target formidable pests and diseases. https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1629313734712-39N61R8DPEQ82C99QMV0/tomatoes.png Biologicals - Biologicals are one of the key drivers of the current evolution in sustainable agriculture and continues to be a rapidly growing market. Agricultural biologicals are a diverse group of products derived from naturally occurring microorganisms and biochemicals that provide solutions as biopesticides and biostimulants. Pebble Labs is focused on microbial biopesticides targeting diseases and pests in food production. https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/0ea97a82-9b13-43b2-ab4d-99e9e7321724/edited+computer.jpg Biologicals - Directed Biotics™ - unlocking the potential of biologicals Pebble Labs is focused on developing microbial biopesticides by precision engineering microbes to deliver RNA molecules that target the most challenging pests and diseases. This next generation of microbial biopesticides, called Directed Biotics™, continuously deliver the powerful and highly specific mode of action of RNAi directly in the targeted tissues of the crop, maximizing efficacy while maintaining the other benefits of microbial pesticides. https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1629243660767-9F16YDSWHIWIEEBUK8LK/4.png Biologicals - Biopesticides and Plant Biostimulants Biopesticides protect plants from pests and diseases with fewer environmental impacts and reduced chemical residues. Plant biostimulants act to stimulate natural processes to enhance nutrient uptake, nutrient efficiency, tolerance to abiotic stress, and crop quality. Growers have increasingly adopted biopesticides and biostimulants in integrated crop management systems because they are compatible with other crop inputs and because they sustainably increase and protect yields while reducing dependence on synthetic chemical pesticides. Biopesticides typically have modes of action that are different from synthetic pesticides, meaning that they have the potential to keep resistance at bay and extend the effective life of all plant protection products. Biopesticides also typically have highly specific modes of action that result in fewer impacts on beneficial insects and a strong safety profile for agricultural workers and consumers. https://www.pebblelabs.com/strategic-partnerships daily 0.75 2024-02-16 https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1629316201993-LY1IXDYK664KSOFCOCQL/image-asset.jpeg Strategic Partnerships - Pebble Labs partners with industry leaders to bring our technology to market https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1629314861574-NUDZM7RFNBX3KIBZ5IPK/GettyImages-1127980299.jpg Strategic Partnerships - Pebble Labs is actively seeking partnerships for our agricultural (crop) opportunities Contributions from Pebble Labs A unique and proprietary approach to deliver the power of RNA to address major food challenges A highly talented research team innovating at the cutting edge of new biological solutions An experienced development team capable of validating the performance of the Directed Biotics™ in ‘real world’ commercial environments A clear strategy towards securing the regulatory approvals for our technology https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/5f019e3a-aa7b-43df-a67e-056d2f9e5c99/4.jpg Strategic Partnerships - Anticipated contributions from strategic partners Joint engagement is product positioning, field validation programs and pre-commercial strategies Joint engagement on product manufacturing including defining and developing product ‘formulations' for key markets A commercial presence (either directly to through local distribution partners) in key markets, including both sales and marketing activities Local support for product approvals and stewardship in key markets https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/8b15b423-f36d-4d92-84d5-747bf4ef249d/edited+teamwork.jpg Strategic Partnerships https://www.pebblelabs.com/terms-of-use-and-privacy-policy daily 0.75 2025-10-01 https://www.pebblelabs.com/news-and-media daily 0.75 2025-10-02 https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/a624ab85-cc77-4367-8580-10d73fe6c6a1/ERIS_Marketplace_Welcome_Packet.png News and Media - Pebble Labs recognized with “Awardable” status in the DARPA ERIS Marketplace Pebble Labs recognized with “Awardable” status in the DARPA ERIS Marketplace 1 October 2025 Pebble Labs, an Ag-Biotech company focused on novel applications of RNA to provide crop protection, today announced that it has achieved “Awardable” status in the DARPA Expedited Research Implementation Series (ERIS) Marketplace. The ERIS Marketplace is a transformative digital platform designed to accelerate acquisition velocity and advance national security innovation. Pebble Labs is creating safe and effective biological-based solutions to protect yields and quality in food production. Pebble Labs harnesses naturally occurring microbes to deliver the power of RNA – and specifically RNAi-based gene silencing technology – to target diseases adversely affecting crops. “We are delighted that the novel RNA-based technology being developed by Pebble Labs – and its ability to provide fast-tracked food security to US farms - was recognized by the DARPA review team” said Dr. Johnny Sena, Chief Scientific Officer of Pebble Labs. “Pebble Labs’ novel use of bacteria that naturally live in the roots of plants is showing significant potential for a number of different crop protection applications.” Pebble Labs was recognized among a competitive field of applicants to the ERIS Marketplace whose solutions demonstrated innovation and potential impact on DoD missions. Learn more at: www.darpaconnect.us/eris Read the full press release here. https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/c8e0450a-7767-4cd0-9555-afcd2ce8eb42/IMG_3976.JPEG News and Media A New Mexico company plans to test a technology that could help eliminate the use of harmful pesticides in farming by "working with nature — not against it." The Directed Biotics technology of Pebble Labs uses molecular biology to create specific RNA molecules in crops and livestock that protect them from pests and disease. Read the full article in the Albuquerque Business Journal. https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/7f03d715-9cfd-486a-98a6-21c890c3dace/Goals+of+Agricultural+Biotech+Infographic+Pebble+Labs+Illustraot-01.png News and Media In our latest infographic, we highlight some of the many goals of agricultural biotech with a focus on sustainably increasing crop yields. Please share widely and help get people excited about this amazing field! https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/94d9cf10-d1f2-4042-997e-5e64b27cb889/RNAi+infographic+-+final-01.png News and Media What do we mean when we say “we’re delivering the power of RNA”? We’re using a programmable form of molecular immunity known as RNAi to protect crops and shrimp from infection. Learn more about RNAi in our new infographic: https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/c30453b6-71dc-4585-89e4-e219d75503fe/edited+lab+coat.jpg News and Media Michelle Pelletier Marshall from GAI profiled Pebble Labs as an up and coming agtech startup in this new Global AgInvesting News feature. https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/8b4ac6cc-26c5-49d3-9b8b-d21613e967a3/pebble-labs-12-01-2021-nm-28682+CROPPED.jpg News and Media The Pebble Labs team won the Better Nutrition Category at the World Food Forum https://www.pebblelabs.com/careers daily 0.75 2025-09-30 https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/4aa2000f-d79d-4bbe-a5d0-6cc98ca26bc7/4.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1629240201651-WHQ2OC7ZUGW1FY7TZ3GT/unsplash-image-ipuJDa_Hzmc.jpg Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/e762cef2-2051-45f6-ae84-e07f78358a37/FullSizeRender.jpg Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/441bb6d2-e1f5-4c40-be65-722482e90381/29.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/cbecf022-da3e-4ecf-b4fc-9299f028303b/18.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/14de930d-048b-445a-b8d7-a9fec7f7e3bd/10.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/9d53ec9e-03e3-44ce-992d-9833e968ccf1/12.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/4f88c369-a63d-4f22-a52a-ea5e105a2158/22.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1629239172194-7DX2GFQIKA8C5F3GOAHL/unsplash-image-zhEk0x9OOhw.jpg Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/5aaf2abe-4b89-470f-ac4c-13f804f97f0c/23.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/ccae6634-a670-4056-bb04-f20ed48c2793/19.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/e0aa642b-20ac-45f8-baf7-69b2ccf59f5a/28.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1629240075257-XBQQ036UZJ8H604H9X3U/unsplash-image-aIYFR0vbADk.jpg Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/2c850359-9308-4277-bdf7-0b2c31dcf3f4/los+alamos+dog.jpeg Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/106d269b-e002-4948-a404-e689a695386c/30.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1013dc4b-f9e3-4267-9d3d-f1f8f2fda7d4/2.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1627775556834-5EOJE7O9V0EB2OG0DH0E/los%2Balamos%2Bsnow.jpg Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/213f18f4-f076-4a36-86f1-9b491d735e99/17.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/293916d2-758d-46c1-8208-b8ccd34f6498/15.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/082c002a-cfad-4c10-b7e0-3f4546b64bc2/27.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/ab0835ab-4003-4b20-99f0-bceedb65ec3b/los+alamos+2.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/f77fb523-0000-45ed-a895-876dcdfb4433/IMG_5407.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/7c21de55-a704-4090-ac15-45fa9d82e9d7/edited+sample.jpg Careers - What we do Pebble Labs is creating safe and effective biological solutions to sustainably protect yields and quality in food production. The key to our Directed Biotics™ technology is delivery - our microbes are precision engineered to safely and effectively provide RNA-based protection against the diseases and pests we are targeting. https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/d9e35d5e-7c7c-4adb-b865-35baeee3acf6/Team+picture.png Careers https://images.squarespace-cdn.com/content/v1/60bd2ab4fbdd3c068cb71e7d/1629300115612-OL5BL3IF1PMBST73CVD8/badlands.png Careers - Why work at Pebble? Pebble Labs is located in the scientific hub of Los Alamos, New Mexico and draws upon the synergy of one of the top laboratories in the United States. Neighboring Santa Fé and Taos communities with their diverse cultural, artistic and music scene, together with outdoors activities including skiing, hiking and fishing in the southern tip of the Rocky Mountains, offers a unique living and family friendly environment.